Supplementary Information Supplementary Table glycans covalently attached on the microarray



Pobieranie 94.5 Kb.
Data07.05.2016
Rozmiar94.5 Kb.


Supplementary Information
Supplementary Table S1. Glycans covalently attached on the microarray. Different categories of glycans on the array are color-coded in column 1 as follows: No color, sialic acid; light blue, α2-3 sialosides; or deep blue, α2-6 sialosides, violet, mixed α2-3/α2-6 biantennaries; green, N-glycolylneuraminic acid-containing glycans; brown, α2-8 linked sialosides; pink, β2-6-linked as well as 9-O-acetylated sialic acids; grey, asialo glycans.

Chart #

Structure

Description

1

α-Neu5Ac

α-Neu5Ac

2

α-Neu5Ac

α-Neu5Ac

3

b-Neu5Ac

β-Neu5Ac

4

Neu5Acα2-3(6-O-Su)Galβ1-4(Fucα1-3)GlcNAcβ

α2-3 so4

5

Neu5Acα2-3Galβ1-3[6OSO3]GalNAcα

α2-3 so4

6

Neu5Acα2-3Galβ1-4[6OSO3]GlcNAcβ

α2-3 so4

7

Neu5Acα2-3Galβ1-4(Fucα1-3)(6OSO3)GlcNAcβ

α2-3 so4

8

Neu5Acα2-3Galβ1-3(6OSO3)GlcNAc

α2-3 so4

9

Neu5Acα2-3Galβ1-3(Neu5Acα2-3Galβ1-4)GlcNAcβ

di-sialoside

10

Neu5Acα2-3Galβ1-3(Neu5Acα2-3Galβ1-4GlcNAcβ1-6)GalNAcβ

di-sialoside

11

Neu5Acα2-3Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-3Galβ1-4GlcNAcβ1­2Manα1-6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-3 biantennary

12

Neu5Acα2-3Galβ

α2-3

13

Neu5Acα2-3GalNAcα

α2-3

14

Neu5Acα2-3Galβ1-3GalNAcα

α2-3

15

Neu5Acα2-3Galβ1-3GlcNAcβ

α2-3

16

Neu5Acα2-3Galβ1-3GlcNAcβ

α2-3

17

Neu5Acα2-3Galβ1-4Glcβ

α2-3

18

Neu5Acα2-3Galβ1-4Glcβ

α2-3

19

Neu5Acα2-3Galβ1-4GlcNAcβ

α2-3

20

Neu5Acα2-3Galβ1-4GlcNAcβ

α2-3

21

Neu5Acα2-3GalNAcβ1-4GlcNAcβ

α2-3

22

Neu5Acα2-3Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ

α2-3

23

Neu5Acα2-3Galβ1-3GlcNAcβ1-3Galβ1-3GlcNAcβ

α2-3

24

Neu5Acα2-3Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ

α2-3

25

Neu5Acα2-3Galβ1-4GlcNAcβ1-3Galβ1-3GlcNAcβ

α2-3

26

Neu5Acα2-3Galβ1-3GalNAcα

α2-3

27

Galβ1-3(Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-6)GalNAcβ

α2-3 fucosylated

28

Neu5Acα2-3Galβ1-3(Fucα1-4)GlcNAcβ

α2-3 fucosylated

29

Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ

α2-3 fucosylated

30

Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ

α2-3 fucosylated

31

Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ

α2-3 fucosylated

32

Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ1-4GlcNAcβ

α2-3 fucosylated

33

Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ1-4(Fucα1-3)GlcNAcβ1­3Galβ1-4(Fucα1-3)GlcNAcβ

α2-3 fucosylated

34

Neu5Acα2-3Galβ1-4GlcNAcβ1-3Galβ1-4(Fucα1-3)GlcNAc

α2-3 fucosylated

35

Neu5Acα2-3(GalNAcβ1-4)Galβ1-4GlcNAcβ

α2-3 internal

36

Neu5Acα2-3(GalNAcβ1-4)Galβ1-4GlcNAcβ

α2-3 internal

37

Neu5Acα2-3(GalNAcβ1-4)Galβ1-4Glcβ

α2-3 internal

38

Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glcβ

α2-3 internal

39

Fucα1-2Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glcβ

α2-3 internal

40

Fucα1-2Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glcβ

α2-3 internal

41

Neu5Acα2-6Galβ1-4[6OSO3]GlcNAcβ

α2-6 so4

42

Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1­6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-6 branched

43

GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-6)Manβ1­4GlcNAcβ1-4GlcNAcβ

α2-6 branched

44

Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1­6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-6 branched

45

Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3(GlcNAcβ1-2Manα1-6)Manβ1­4GlcNAcβ1-4GlcNAcβ

α2-6 branched

46

Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1­2Manα1-6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-6 biantenary

47

Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1­2Manα1-6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-6 biantenary

48

Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1­2Manα1-6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-6 biantenary

49

Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3(Galβ1-4GlcNAcβ1-2Manα1­6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-6 biantenary

50

Neu5Acα2-6GalNAcα

α2-6

51

Neu5Acα2-6Galβ

α2-6

52

Neu5Acα2-6Galβ1-4Glcβ

α2-6

53

Neu5Acα2-6Galβ1-4GlcNAcβ

α2-6

54

Neu5Acα2-6Galβ1-4GlcNAcβ

α2-6

55

Neu5Acα2-6GalNAcβ1-4GlcNAcβ

α2-6

56

Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ

α2-6

57

Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ1­4(Fucα1-3)GlcNAcβ

α2-6 + fucosylation

58

Galβ1-3(Neu5Acα2-6)GlcNAcβ1-3Galβ1-4Glcβ

α2-6 internal

59

Galβ1-3(Neu5Acα2-6)GalNAcα

α2-6 internal

60

Neu5Acα2-3Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-6Galβ1-4GlcNAcβ1­2Manα1-6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-3/6 biantennary

61

Neu5Acα2-6Galβ1-4GlcNAcβ1-2Manα1-3(Neu5Acα2-3Galβ1-4GlcNAcβ1­2Manα1-6)Manβ1-4GlcNAcβ1-4GlcNAcβ

α2-3/6 biantennary

62

Neu5Acα2-3Galβ1-3(Neu5Acα2-6)GalNAc

α2-3/6 disialoside

63

Neu5Acα2-3Galβ1-3(Neu5Acα2-6)GalNAcα

α2-3/6 disialoside

64

Neu5Acα2-3(Neu5Acα2-6)GalNAcα

α2-3/6 disialoside

65

Neu5Gcα

Neu5Gc α

66

Neu5Gcα2-3Galβ1-3(Fucα1-4)GlcNAcβ

Neu5Gc α2-3

67

Neu5Gca2-3Galβ1-3GlcNAcβ

Neu5Gc α2-3

68

Neu5Gcα2-3Galβ1-4(Fucα1-3)GlcNAcβ

Neu5Gc α2-3

69

Neu5Gcα2-3Galβ1-4GlcNAcβ

Neu5Gc α2-3

70

Neu5Gcα2-3Galβ1-4Glcβ

Neu5Gc α2-3

71

Neu5Gcα2-6GalNAcα

Neu5Gc α2-6

72

Neu5Gcα2-6Galβ1-4GlcNAcβ

Neu5Gc α2-6

73

Neu5Acα2-8Neu5Acα

Neu5Ac α2-8

74

Neu5Acα2-8Neu5Acα2-8Neu5Acα

Neu5Ac α2-8

75

Neu5Acα2-8Neu5Acα2-3(GalNAcβ1-4)Galβ1-4Glcβ

Neu5Ac α2-8 α2-3

76

Neu5Acα2-8Neu5Acα2-3Galβ1-4Glcβ

Neu5Ac α2-8 α2-3

77

Neu5Acα2-8Neu5Acα2-8Neu5Acα2-3(GalNAcβ1-4)Galβ1-4Glcβ

Neu5Ac α2-8 α2-8 α2-3

78

Neu5Acα2-8Neu5Acα2-8Neu5Acα2-3Galβ1-4Glcβ

Neu5Ac α2-8 α2-8 α2-3

79

Neu5Acα2-8Neu5Acα

Neu5Ac α2-8

80

Neu5Acα2-8Neu5Acβ

Neu5Ac α2-8

81

Neu5Acα2-8Neu5Acα2-8Neu5Acβ

Neu5Ac α2-8 α2-8

82

Neu5Acβ2-6GalNAcα

β2-6

83

Neu5Acβ2-6Galβ1-4GlcNAcβ

β2-6

84

Neu5Gcβ2-6Galβ1-4GlcNAc

β2-6

85

Galβ1-3(Neu5Acβ2-6)GalNAcα

β2-6

86

9NAcNeu5Aca

9NAcNeu5

87

9NAcNeu5Acα2-6Galβ1-4GlcNAcβ

9NAcNeu5

88

Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ

asialo

89

Galβ1-3GlcNAcβ1-3Galβ1-3GlcNAcβ

asialo

90

Fucα1-2Galβ1-3GlcNAcβ1-3Galβ1-4Glcβ

asialo

91

Fucα1-2Galβ1-4(Fucα1-3)GlcNAcβ1-3Galβ1-4(Fucα1-3)GlcNAcβ

asialo

92

GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAcβ

asialo

93

GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAcβ

asialo

94

Galα1-3(Fucα1-2)Galβ1-3GlcNAcβ

asialo

95

Galα1-3(Fucα1-2)Galβ1-4(Fucα1-3)GlcNAcβ

asialo

96

Galβ1-3GalNAc

asialo


Key: Neu5Ac = Sialic acid

Neu5Gc = N-glycolylneuraminic acid

OSO3 = sulfate; Gal = galactose

Fuc = fucose

GlcNAc = N-acetyl-D-glucosamine

GalNAc = N-acetyl-D-galactosamine

Glc = D-glucose

Man = D-mannose



9NAc = 9-O-acetyl









©absta.pl 2019
wyślij wiadomość

    Strona główna